すべては患者さんの笑顔のために ~京都大学消化管外科~
京都大学医学部附属病院 消化管外科 
TEL:075-751-3111(病院代表)

論文業績

2018年からの当教室 英語論文のみを掲載しております。

2024年

  • Nishigori T, Kumamaru H, Obama K, Suda K, Tsunoda S, Yoda Y, et al. Short-term outcomes of robot-assisted versus conventional minimally invasive esophagectomy: A propensity score-matched study via a nationwide database. Ann Gastroenterol Surg. 2024; 00: 1–10. https://doi.org/10.1002/ags3.12854
  • Fujita, Y., Hida, K., Hoshino, N. et al. Laparoscopic vs. open surgery for rectal cancer in patients with obesity: short-term outcomes and relapse-free survival across age groups. Surg Today (2024). https://doi.org/10.1007/s00595-024-02901-2
  • Okamura R, Aoyama R, Tsunoda S, Yamashita Y, Hata H, Kinjo Y, Miki A, Kanaya S, Yamamoto M, Matsuo K, Manaka D, Tanaka E, Kawada H, Kondo M, Itami A, Kan T, Kadokawa Y, Ito T, Jikihara S, Kasahara K, Sakamoto T, Okumura S, Maekawa H, Nishigori T, Hisamori S, Obama K. Management challenges and the role of adjuvant chemotherapy in remnant gastric cancer: an analysis of 313 patients from the KEGG multicenter observational study. Gastric Cancer. 2024 Aug 8. doi: 10.1007/s10120-024-01544-z. Epub ahead of print. PMID: 39115631.
  • Okamoto M, Okamura R, Itatani Y, et al. Low-grade appendiceal mucinous neoplasm penetrating sigmoid colon: A case report. Asian J Endosc Surg. 2024; 17(4):e13368. doi:10.1111/ases.13368
  • Kiyasu, Y., Poudel, S., Koike, D. et al. Current status of the surgical training system in Japan: results of a nationwide questionnaire survey of graduating surgical trainees. Surg Today (2024). https://doi.org/10.1007/s00595-024-02884-0
  • Ueno, K., Nishigori, T., Tokoro, Y. et al. The efficacy of simple oral nutritional supplements versus usual care in postoperative patients with gastric cancer: study protocol for a multicenter, open-label, parallel, randomized controlled trial. Trials 25, 445 (2024). https://doi.org/10.1186/s13063-024-08169-8
  • Masui, H., Kawada, K., Inamoto, S. et al. Laparoscopic redo surgery for sigmoid volvulus following laparoscopic sigmoidectomy. surg case rep 10, 163 (2024). https://doi.org/10.1186/s40792-024-01961-3
  • Fujii Y, Hida K, Sugimoto A, Nishijima R, Fujimoto M, Hoshino N, Maekawa H, Okamura R, Itatani Y, Obama K. Appendiceal neoplasms derived from appendiceal tip remnants following appendectomy: a report of two cases. Surg Case Rep. 2024 Jun 13;10(1):144. doi: 10.1186/s40792-024-01936-4. PMID: 38867137; PMCID: PMC11169428.
  • Hirata, W., Itatani, Y., Hida, K. et al. Robot-assisted extended rectal anterior resection for peritoneal dissemination of hepatocellular carcinoma invading rectum after atezolizumab plus bevacizumab combined therapy. Int Canc Conf J (2024). https://doi.org/10.1007/s13691-024-00688-0
  • Horita K, Hida K, Itatani Y, Fujita H, Hidaka Y, Yamamoto G, Ito M, Obama K. Real-time detection of active bleeding in laparoscopic colectomy using artificial intelligence. Surg Endosc. 2024 May 17. doi: 10.1007/s00464-024-10874-z. Epub ahead of print. PMID: 38760565.
  • Morimoto, T., Hisamori, S., Kinoshita, H. et al. A case of laparoscopic lymphadenectomy for adenocarcinoma of unknown primary incidentally detected as a solitary enlarged lymph node along the common hepatic artery. surg case rep 10, 91 (2024). https://doi.org/10.1186/s40792-024-01888-9
  • Yoshida S, Fujii Y, Hoshino N, Tokoro Y, Tsunoda S, Obama K, Watanabe N. Anterior versus posterior mediastinal reconstruction after esophagectomy in esophageal cancer patients: a systematic review and meta-analysis. Langenbecks Arch Surg. 2024 Mar 8;409(1):88. doi: 10.1007/s00423-024-03279-y. PMID: 38456948.
  • Articulating forceps in laparoscopic total mesorectal excision: A video comparison with robotic surgery”Masui H, Itatani Y, Hoshino N, et al. Articulating forceps in laparoscopic total mesorectal excision: A video comparison with robotic surgery. Asian J Endosc Surg. 2024; 17(2):e13281. doi:10.1111/ases.13281
  • “Utility of articulating instruments as an alternative to robotic devices in laparoscopic right hemicolectomy”Sakamoto, Y., Itatani, Y., Nishiyama, K. et al. Utility of articulating instruments as an alternative to robotic devices in laparoscopic right hemicolectomy. Int Canc Conf J (2024). https://doi.org/10.1007/s13691-024-00654-w
  • “Prediction for oxaliplatin-induced liver injury using patient-derived liver organoids”
    Tatsumi K, Wada H, Hasegawa S, Asukai K, Nagata S, Ekawa T, Akazawa T, Mizote Y, Okumura S, Okamura R, Ohue M, Obama K, Tahara H. Prediction for oxaliplatin-induced liver injury using patient-derived liver organoids. Cancer Med. 2024 Feb;13(3):e7042. doi: 10.1002/cam4.7042. PMID: 38400666; PMCID: PMC10891453.
  • Sakahara M, Okamoto T, Srivastava U, Natsume Y, Yamanaka H, Suzuki Y, Obama K, Nagayama S, Yao R. Paneth-like cells produced from OLFM4+ stem cells support OLFM4+ stem cell growth in advanced colorectal cancer. Commun Biol. 2024 Jan 5;7(1):27. doi: 10.1038/s42003-023-05504-8. PMID: 38182890; PMCID: PMC10770338.

2023年

  • Hirata W, Itatani Y, Masui H, Kawada K, Mizuno R, Yamamoto T, Okamoto T, Ogawa R, Inamoto S, Maekawa H, Okamura R, Kiyasu Y, Hanada K, Okamoto M, Nishikawa Y, Sugimoto N, Tamura T, Hatano E, Sakai Y, Obama K.
    Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage. Sci Rep. 2023 Dec 14;13(1):22217. doi: 10.1038/s41598-023-49312-w. PMID: 38097649; PMCID: PMC10721637.
  • Ishiguro Yoshitaka, Iriguchi Shoichi, Asano Shinya, Shinohara Tokuyuki, Shiina Sara, Arima Suguru, Kassai Yoshiaki, Sakai Yoshiharu, Obama Kazutaka, Kaneko Shin,
    Lineage tracing of T cell differentiation from T-iPSC by 2D feeder-free culture and 3D organoid culture, Frontiers in Immunology, VOLUME=14 2023
  • Nobuaki Hoshino, Koya Hida, Yudai Fukui, Yoshimitsu Takahashi, Takeo Nakayama, Kazutaka Obama,
    Impact of diverting stoma on long-term survival in patients with rectal cancer: A nationwide study based on health insurance claims data,
    Clinical Surgical Oncology, Volume 2, Issue 4, 2023, 100030, ISSN 2773-160X
  • Analysis of the characteristics and outcomes of patients with pseudomyxoma peritonei of appendiceal origin treated with curative-intent surgery.
    Kamada Y, Hida K, Yonemura Y, Nakakura A, Kitai T, Mizumoto A, Yoshida S, Tokoro Y, Obama K. Analysis of the characteristics and outcomes of patients with pseudomyxoma peritonei of appendiceal origin treated with curative-intent surgery. Surg Oncol. 2023 Nov 5;51:102012. doi: 10.1016/j.suronc.2023.102012. Epub ahead of print. PMID: 37972508.
  • Okamura R, Itatani Y, Fujita Y, Hoshino N, Okumura S, Nishiyama K, Hida K,Obama K. Postoperative recurrence in locally advanced rectal cancer: how does neoadjuvant treatment affect recurrence pattern? World J Surg Oncol. 2023 Aug16;21(1):247. doi: 10.1186/s12957-023-03136-0. PMID: 37587422; PMCID:PMC10428603.
  • Yoshida S, Nishigori T, Maekawa H, Hoshino N, Hisamori S, Tsunoda S, Kobayashi A, Nobori Y, Shide K, Inagaki N, Obama K. Total gastrectomy as a risk factor for postoperative loss of skeletal muscle in minimally invasive surgery for patients with gastric cancer. Asian J Endosc Surg. 2023 Jul 31. doi: 10.1111/ases.13233. Epub ahead of print. PMID: 37524325.
  • Jikihara S, Hoshino N, Hida K, Inamoto S, Tanaka E, Matsusue R, Hamasu S, Matsuo K, Hashida H, Shiota T, Yamada M, Yamashita Y, Nakamura Y, Yoshitomi M, Murakami T, Itatani Y, Hisamori S, Tsunoda S, Obama K. Impact of the coronavirus disease 2019 pandemic on gastric and colorectal cancer surgeries: a multicenter epidemiologic study from the Kinki region of Japan. Surg Today. 2023 Aug 10. doi: 10.1007/s00595-023-02734-5. Epub ahead of print. PMID: 37561204.
  • Ueno K, Horita K, Hoshino N, Hida K, Watanabe N. Extensive intraoperative peritoneal lavage for resectable advanced gastric cancer. Cochrane Database of Systematic Reviews 2023, Issue 7. Art. No.: CD014950. DOI: 10.1002/14651858.CD014950. Accessed 18 July 2023.
  • Kinoshita H, Nishigori T, Nakabe T, et al. Factors Associated With Postoperative Decisional Regret in Patients Undergoing Gastrointestinal Cancer Surgery: A Prospective Cohort Study. The American SurgeonTM. 2023;0(0). doi:10.1177/00031348231184197
  • Kinoshita, H, Nishigori, T, Kunisawa, S, Hida, K, Hosogi, H, Inamoto, S, et al. Identification of complications requiring interventions after gastrointestinal cancer surgery from real-world data: An external validation study. Ann Gastroenterol Surg. 2023; 00: 1– 10. https://doi.org/10.1002/ags3.12704
  • Gunji D, Narumi R, Muraoka S, Isoyama J, Ikemoto N, Ishida M, Tomonaga T, Sakai Y, Obama K, Adachi J. Integrative analysis of cancer dependency data and comprehensive phosphoproteomics data revealed the EPHA2-PARD3 axis as a cancer vulnerability in KRAS-mutant colorectal cancer. Mol Omics. 2023 May 26. doi: 10.1039/d3mo00042g. Epub ahead of print. PMID: 37232035.
  • Kawada K, Okada T, Fukumoto M, Obama K. Laparoscopic Radical Surgery for Right-Sided Colon Cancer With Lymph Node Metastasis in the Gastrocolic Ligament. Dis Colon Rectum. 2023 Jun 1;66(6):e291. doi: 10.1097/DCR.0000000000002609. Epub 2023 Mar 6. PMID: 36892463.
    ※ https://journals.lww.com/dcrjournal/pages/video.aspx?v=543
  • Morimoto T, Takemura Y, Miura T, Yamamoto T, Kakizaki F, An H, Maekawa H, Yamaura T, Kawada K, Sakai Y, Yuba Y, Terajima H, Obama K, Taketo MM, Miyoshi H. Novel and efficient method for culturing patient-derived gastric cancer stem cells. Cancer Sci. 2023 May 20. doi: 10.1111/cas.15840. Epub ahead of print. PMID: 37208931.
  • Kinoshita H, Shimoike N, Nishizaki D, Hida K, Tsunoda S, Obama K, Watanabe N. Routine decompression by nasogastric tube after oesophagectomy for oesophageal cancer (Protocol). Cochrane Database of Systematic Reviews 2023, Issue 2. Art. No.: CD014751. DOI: 10.1002/14651858.CD014751.
  • Murakami K, Hoshino N, Hida K, Obama K, Sakai Y, Watanabe N. Closure of mesenteric defects for prevention of internal hernia a&er Roux-en-Y gastric bypass in bariatric surgery (Protocol). Cochrane Database of Systematic Reviews 2023, Issue 5. Art. No.: CD014612. DOI: 10.1002/14651858.CD014612.
  • Nishizaki, D., Fujita, Y., Sakamoto, T. et al. What can surgeons do to prevent job leave soon after cancer diagnosis? A brief report on colorectal cancer survivors in Japan. Support Care Cancer 31, 331 (2023). https://doi.org/10.1007/s00520-023-07796-2
  • Kawada, K., Horie, A., Itatani, Y., Kawamoto, K., Mandai, M. and Obama, K. (2023), Robotic posterior pelvic exenteration for a huge rectal gastrointestinal stromal tumour – A video vignette. Colorectal Dis. https://doi.org/10.1111/codi.16596
  • Comparison of Cytoreductive Surgery and Resection of Isolated Peritoneal Metastases in Patients with Peritoneal Metastases from Colorectal Cancer: A Retrospective Study.
    Yoshida S, Kamada Y, Hida K, Okada K, Obama K, Morita S, Kitai T, Yonemura Y. J Anus Rectum Colon. 2023 Apr 25;7(2):91-101. doi: 10.23922/jarc.2022-065. eCollection 2023. PMID: 37113582
  • Impact of laparoscopic surgery on short-term and long-term outcomes in elderly obese patients with colon cancer.
    Hoshino, N, Hida, K, Fujita, Y, Ohira, M, Ozawa, H, Bando, H, et al. Ann Gastroenterol Surg. 2023; 00: 1– 8. https://doi.org/10.1002/ags3.12678
  • Efficacious Combination Drug Treatment for Colorectal Cancer That Overcomes Resistance to KRAS G12C Inhibitors.
    Matsubara H, Miyoshi H, Kakizaki F, Morimoto T, Kawada K, Yamamoto T, Obama K, Sakai Y, Taketo MM.
    Mol Cancer Ther. 2023 Apr 3;22(4):529-538. doi: 10.1158/1535-7163.MCT-22-0411.
    PMID: 36780229
  • Total pelvic exenteration for mucinous adenocarcinoma arising from an implantation cyst 26 years after surgery for rectal cancer.
    Fujita Y, Itatani Y, Kawada K, Sumiyoshi T, Akamatsu S, Tsuge I, Okada T, Fujimoto M, Okamoto T, Nishiyama K, Kasahara K, Okumura S, Okamura R, Maekawa H, Nishigori T, Hoshino N, Hisamori S, Tsunoda S, Hida K, Obama K.
    Asian J Endosc Surg. 2023 Mar 7. doi: 10.1111/ases.13178. Online ahead of print.
    PMID: 36882944
  • Comparison of Minimally Invasive Surgery with Open Surgery for Remnant Gastric Cancer: A Multi-institutional Cohort Study.
    Aoyama R, Tsunoda S, Okamura R, Yamashita Y, Hata H, Kinjo Y, Miki A, Kanaya S, Yamamoto M, Matsuo K, Manaka D, Tanaka E, Kawada H, Kondo M, Itami A, Kan T, Kadokawa Y, Ito T, Hirai K, Hosogi H, Nishigori T, Hisamori S, Hoshino N, Hida K, Goto Y, Nakayama T, Obama K.
    Ann Surg Oncol. 2023 Feb 18. doi: 10.1245/s10434-023-13232-w. Online ahead of print.
    PMID: 36808589
  • Hoshino, N, Hida, K, Yoshida, S, Ueno, K, Noguchi, T, Ishihara, S, et al. Postoperative complications and prognosis based on type of surgery in ulcerative colitis patients with colorectal cancer: A multicenter observational study of data from the Japanese Society for Cancer of the Colon and Rectum. Ann Gastroenterol Surg. 2023; 00: 1– 11. https://doi.org/10.1002/ags3.12659

2022年

  • Differential involvement of LUBAC-mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation.
    Sakamoto Y, Sasaki K, Omatsu M, Hamada K, Nakanishi Y, Itatani Y, Kawada K, Obama K, Seno H, Iwai K.
    J Pathol. 2022 Dec 1. doi: 10.1002/path.6042. Online ahead of print.
    PMID: 36454102
  • A Simple Preparation Method of Gelatin Hydrogels Incorporating Cisplatin for Sustained Release
    Takahisa Suzuki, Shigeru Tsunoda,Kota Yamashita,Toshie Kuwahara, Mitsuru Ando,Yasuhiko Tabata and Kazutaka Obama
    Pharmaceutics 2022, 14(12), 2601; https://doi.org/10.3390/pharmaceutics14122601
  • Kasahara K, Narumi R, Nagayama S, Masuda K, Esaki T, Obama K, Tomonaga T, Sakai Y, Shimizu Y, Adachi J. A large-scale targeted proteomics of plasma extracellular vesicles shows utility for prognosis prediction subtyping in colorectal cancer. Cancer Med. 2022 Nov 16. doi: 10.1002/cam4.5442. Epub ahead of print. PMID: 36394150.
  • A case of long-term survival treated with three metastasectomies and two subsequent adjuvant nivolumab therapies for recurrent malignant melanoma of the esophagus. Hanada K, Tsunoda S, Nomura M, Fujimura S, Yutaka Y, Nishigori T, Hisamori S, Maekewa H, Hoshino N, Itami A, Tanaka E, Obama K. Surg Case Rep. 2022 Nov 4;8(1):206. doi: 10.1186/s40792-022-01561-z. PMID: 36333558; PMCID: PMC9636353.
  • Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells. Nishikawa G, Kawada K, Hanada K, Maekawa H, Itatani Y, Miyoshi H, Taketo MM, Obama K. Cells. 2022 Oct 18;11(20):3273. doi: 10.3390/cells11203273. PMID: 36291140; PMCID: PMC9600002.
  • Robotic Posterior Exenteration for Locally Advanced Rectal Cancer with Rectovaginal Fistula. Kenji Kawada, Yoshiro Itatani, Akihito Horie, Hiroki Yamanaka, Koji Yamanoi, Keiko Kasahara, Daiju Yokoyama, Shintaro Okumura, Koya Hida, Kazutaka Obama. Ann Surg Oncol. 2022 Aug 23. PMID: 35999413 DOI: 10.1245/s10434-022-12158-z
  • Combined laparoscopic and transperineal total pelvic exenteration for recurrent rectal cancer-a video vignette. Kenji Kawada, Keita Hanada, Daiju Yokoyama, Shusuke Akamatsu, Takayuki Goto, Kazutaka Obama. Colorectal Dis. 2022 Aug 24. PMID: 36000801 DOI: 10.1111/codi.16308
  • Laparoscopic redo coloanal anastomosis for rectovaginal fistula following transanal total mesorectal excision – a video vignette. Keita Hanada, Kenji Kawada, Tomoaki Okada, Koji Yamanoi, Masaki Mandai, Kazutaka Obama. Colorectal Dis. 2022 Aug 25. PMID: 36004559 DOI: 10.1111/codi.16310
  • Prophylactic supraclavicular lymph node dissection for esophageal squamous cell carcinoma: a systematic review and meta-analysis,
    Shigeru Tsunoda, Nobuaki Hoshino, Shinya Yoshida, Kazutaka Obama. Surg Today. 2022 Jul 7. PMID: 35798906 DOI: 10.1007/s00595-022-02544-1
  • Single-incision laparoscopic partial cecectomy for appendiceal mucocele in a patient with porphyria photosensitivity.
  • Takuya Takami, Yoshiro Itatani, et.al., Asian J Endosc Surg. 2022 Jul 3. PMID: 35781071 DOI: 10.1111/ases.13102
  • Strangulated small bowel obstruction caused by isolated obturator nerve and pelvic vessels after pelvic lymphadenectomy in gynecologic surgery: two case reports.
  • Ideyama R, Okuchi Y, et. al., Surg Case Rep. 2022 May 30;8(1):104. doi: 10.1186/s40792-022-01459-w. PMID: 35644816
  • Correlation between Colon Perfusion and Postoperative Fecal Output through a Transanal Drainage Tube during Laparoscopic Low Anterior Resection, Cancers (Basel). 2022 May 8;14(9):2328. doi: 10.3390/cancers14092328. PMID: 35565456
  • Robotic supralevator total pelvic exenteration with lateral pelvic sidewall dissection for rectal cancer, Tech Coloproctol. 2022 May 16. doi: 10.1007/s10151-022-02625-w. Online ahead of print. PMID: 35576084
  • Prevalence and safety of robotic surgery for gastrointestinal malignant tumors in Japan, Annals of Gastroenterological Surgery, 2022 May 17. doi: 10.1002/ags3.12579
  • Establishment and validation of a nomogram for predicting potential lateral pelvic lymph node metastasis in low rectal cancer, Int J Clin Oncol. 2022 Apr 12. doi: 10.1007/s10147-022-02157-1. PMID: 35415787
  • Safety assessment of robotic gastrectomy and analysis of surgical learning process: a multicenter cohort study, Gastric Cancer. 2022 Apr 13. doi: 10.1007/s10120-022-01289-7. PMID: 35416523
  • Development and evaluation of a colorectal cancer screening method using machine learning-based gut microbiota analysis. Cancer Med. 2022 Mar 22.DOI: 10.1002/cam4.4671  PMID: 35318827
  • ARID1A loss-of-function induces CpG island methylator phenotype. Cancer Lett. 2022 Feb 5. DOI: 10.1016/j.canlet.2022.215587. PMID: 35131383
  • Clinical Benefits of Routine Feeding Jejunostomy Tube Placement in Patients Undergoing Esophagectomy. J Gastrointest Surg. 2022 Feb 9. doi: 10.1007/s11605-022-05265-5 PMID: 35141836
  • Oncologic benefit of adjuvant chemotherapy for locally advanced rectal cancer after neoadjuvant chemoradiotherapy and curative surgery with selective lateral pelvic lymph node dissection: An international retrospective cohort study. Eur J Surg Oncol
    . 2022 Feb 3. doi: 10.1016/j.ejso.2022.01.030 PMID: 35153105
  • Laparoscopic posterior pelvic exenteration for clear cell adenocarcinoma arising in an episiotomy scar. Asian J Endosc Surg. 2022 Jan 27. doi: 10.1111/ases.13033. PMID: 35086165
  • McKeown esophagectomy with concomitant median arcuate ligament release in a case of esophageal cancer with celiac artery stenosis. Surg Case Rep. 2022 Jan 7;8(1):5. doi: 10.1186/s40792-022-01359-z.

2021年

  • Total gastrectomy with splenectomy versus total gastrectomy alone for gastric cancer(Protocol).
    Cochrane Database Syst Rev: Fujita Y, 12;CD014601, 2021
  • Laparoscopic Surgery for Acute Diffuse Peritonitis Due to Gastrointestinal Perforation: A Nationwide Epidemiologic Study Using the National Clinical Database, Hoshino N, Ann Gastroenterol Surge (2021)
  • Anterior versus posterior mediastinal reconstruction after esophagectomy for patients with esophageal cancer (Protocol). Cochrane Database Syst Rev:Yoshida S, 12;CD014607, 2021
  • Relationship between diverting stoma and adjuvant chemotherapy in patients with rectal cancer: a nationwide study using the National Database of Health Insurance Claims and Specific Health Checkups of Japan, Hoshino N, Int J Clin Oncol (2021)
  • Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion, Okumura S, Nat Commun 12, 5674, 2021.
  • Mesenteric closure after laparoscopic total gastrectomy with Roux‑en‑Y reconstruction is effective for prevention of internal hernia: a multicenter retrospective study. Murakami K, Surgical Endoscopy ,2021
  • Laparoscopic surgery for median arcuate ligament syndrome using real-time stereotactic navigation. Aisu Y, Asian J Endosc Surg. 2021;1-6. doi:10.1111/ases.12990
  • Dual blockade of macropinocytosis and asparagine bioavailability shows synergistic anti-tumor effects on KRAS-mutant colorectal cancer: Hanada K, Cancer Lett. Sep 17:S0304-3835(21)00471-7. 2021.
  • Roux-en-Y versus Billroth-I reconstruction aer distal gastrectomy for gastric cancer (Review)
    Cochrane Database Syst Rev:Nishizaki D, 15;9:CD012998, 2021
  • Inflammation-Related Biomarkers for the Prediction of Prognosis in Colorectal Cancer Patients. Yamoto T, Int J Mol Sci. 22(15):8002, 2021.
  • Long-Term Outcomes of Laparoscopic Radical Gastrectomy for Highly Advanced Gastric Cancer: Final Report of a Prospective Phase II Trial (KUGC04). Hisamori S, Ann Surg Oncol, 2021.
  • Chronological Changes in Skeletal Muscle Mass Two Years after Minimally Invasive Esophagectomy: A Prospective Cohort Study:Yoshida S, Surgical Endoscopy ,2021
  • Comparative Outcomes of Laparoscopic Gastrectomy and Open Gastrectomy for Scirrhous Gastric Cancer: A Multicenter Retrospective Cohort Study:Fujita Y, Ann surg Open,2021
  • PTEN is a predictive biomarker of trastuzumab resistance and prognostic factor in HER2-overexpressing gastroesophageal adenocarcinoma:Yokoyama D, NaturePortfolio,1,11,9013,2021
  • Survival benefit of adjuvant chemotherapy in elderly patients with colon cancer: a systematic review and meta-analysis:Hoshino N, Int J Clin Oncol,2021
  • Similarities and differences between study designs in short and long-term outcomes of laparoscopic versus open low anterior resection for rectal cancer: A systematic review and meta-analysis of randomized, case-matched, and cohort studies:Hoshino N, Ann Gastroenterol Surg,2021
  • Combination of lymphocyte count and albumin concentration as a new prognostic biomarker for rectal cancer:Yamamoto T, Sci Rep,,11,5027,2021
  • Simple technique of azygos arch division and retraction for minimally invasive esophagectomy:Tsunoda S, Esophagus,1,18,169-172,2021
  • ASO Author Reflections: Clinical Benefit of Robot-Assisted Minimally Invasive Esophagectomy over Conventional Minimally Invasive Esophagectomy:Tsunoda S, Ann Surg Oncol,2,28,648-649,2021
  • Lower Incidence of Postoperative Pulmonary Complications Following Robot-Assisted Minimally Invasive Esophagectomy for Esophageal Cancer: Propensity Score-Matched Comparison to Conventional Minimally Invasive Esophagectomy:Tsunoda S, Ann Surg Oncol,2,28,639-647,2021
  • Colorectal Cancer–Derived CAT1-Positive Extracellular Vesicles Alter Nitric Oxide Metabolism in Endothelial Cells and Promote Angiogenesis:Ikeda A, Mol Can Res,5,19,834-846,2021
  • Impact of postoperative complications after primary tumor resection on survival in patients with incurable stage IV colorectal cancer: A multicenter retrospective cohort study:Fujita Y, Ann Gastroenterol Surg,5,354–362,2021
  • Effect of herbal medicine daikenchuto on gastrointestinal symptoms following laparoscopic colectomy in patients with colon cancer: A prospective randomized study:Hanada K, Biomedicine & Pharmacotherapy ,141,2021
  • The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells:Ito TCOMMUNICATIONS BIOLOGY,2021
  • Direct percutaneous access to a mesenteric vein for antegrade embolization of esophageal varices: A case report:Onishi Y, Radiology Case Reports,16,2491-95,2021
  • Prognostic impact of lateral pelvic node dissection on the survival of patients in low rectal cancer subgroups based on lymph node size:Hida K, Annals of Surgical Oncology,2021

2020年

  • Subcuticular sutures for skin closure in non-obstetric surgery (Review)Cochrane Database Syst Rev:Goto S, 4(4),CD012124, 2020.
  • Iatrogenic diaphragmatic hernia as a late complication of laparoscopic excisional biopsy of peritoneal nodules: A case report., Hashimoto K, Int J Surg Case Rep,67,169-172,2019
  • Expression of TIM3/VISTA Checkpoints and the CD68 Myeloid Suppression Marker Correlates with Anti-PD1/PDL1 Resistance: Implications of Immunogram Heterogeneity,Okamura R , (contributed equally as first authors),Oncoimmunology,9(1),2020
  • ARID1A alterations function as a biomarker for longer progression-free survival after anti-PD-1/PD-L1 immunotherapy,Okamura R, Journal for ImmunoTherapy of Cancer,8(1),2020
  • Temporal and Spatial Effects and Survival Outcomes Associated with Concordance between Tissue and Blood KRAS Alterations in the Pan-Cancer Setting,Mardinian K and Okamura R, (contributed equally),International Journal of Cancer,146(2),566-576,2020
  • Three-dimensional Morphogenesis of the Omental Bursa From Four Recesses in Staged Human Embryos,Nakamura T, J Anat. ,2020
  • Disruption of CCR1-mediated myeloid cell accumulation suppresses colorectal cancer progression in mice., Kiyasu Y, Cancer Lett.,487,53-62,2020
  • Use of a lighted stent to avoid urethral injury during robotic intersphincteric resection for secondary rectal cancer following prior radiotherapy to prostate cancer– a video vignette,Kawada K, Colorectal Dis,22(10),1460-1461,2020
  • Prediction of surgical difficulty in mini-invasive surgery for rectal cancer by using MRI pelvimetry,Yamamoto T, BJS Open,2020
  • Combined robotic and cystoscopic surgery for rectal cancer invading urinary bladder,Kawada K, Int Cancer Conf J,9,102-106,2020
  • Laparoscopic abdominoperineal resection following revascularization of iliac vessels – a video vignette,Kawada K, Colorectal Dis,2020
    Utility of a lighted stent to avoid male urethral injury in transanal rectal surgery,Kawada K, Mini-invasive Surg.,4,7,2020
  • Stereotactic navigation for rectal surgery: comparison of 3D C-arm−based registration to paired-point registration,Okada T, Dis Colon Rectum. ,63(5),693-700,2020
  • Assessment of body composition and impact of sarcopenia and sarcopenic obesity in patients with gastric cancer,Nishigori T, Transl Gastroenterol Hepatol ,2020
  • Utility of ICG fluorescence imaging with vessel clamp for ileocecal resection while preserving ileal conduit constructed after previous total cystectomy,Okada T, Surgical Case Reports,6(257),2020
  • “Wnt-modified materials mediate asymmetricstem cell division to direct human osteogenic
    tissue formation for bone repair,Okuchi Y, Nature Materials,2020″
  • Suppressing neutrophil-dependent angiogenesis abrogates resistance to anti-VEGF antibody in a genetic model of colorectal cancer,Itatani Y, PNAS,117(35),21598-21608,2020
  • Robotic versus laparoscopic surgery for gastric cancer: an overview of systematic reviews with quality assessment of current evidence. ,Hoshino N, Updates Surg.,72(3),573-582,2020
  • Emergency surgery for gastrointestinal cancer: A nationwide study in Japan based on the National Clinical Database.,Hoshino N, Ann Gastroenterol Surg.,4,549-561,2020
  • Prediction of surgical difficulty in minimally invasive surgery for rectal cancer by use of MRI pelvimetry.,Yamamoto T, BJS Open,4(4),666-677,2020
  • Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy.,Yamamoto T, Cancers,12,E2010,2020
  • Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy, Oshima N, Cell Reports,30,1798-1810,2020
  • Robotic gastric mobilization in robotic minimally invasive esophagectomy.,Tsunoda S, J Thorac Dis,12,(7),3457-3459,2020
  • Mesenteric excision of upper esophagus: a concept for rational anatomical lymphadenectomy of the recurrent laryngeal nodes in thoracoscopic esophagectomy.,Tsunoda S, Surg Endosc.,34(1),133-141,2020
  • Laparoscopic left hemicolectomy with regional lymph node navigation and intracorporeal anastomosis for splenic flexure colon cancer,Itatani Y, International Cancer Conference Journal ,2020

2019年

  • The effects of intraoperative ICG fluorescence angiography in laparoscopic low anterior resection: a propensity score-matched study.、Wada T, Int J Clin Oncol、24(4),394-402,2019
  • Diagnostic accuracy of magnetic resonance imaging and computed tomography for lateral lymph node metastasis in rectal cancer: a systematic review and meta-analysis.、Hoshino N, Int J Clin Oncol、24(1),46-52,2019
  • Cancer cell niche factors secreted from cancer-associated fibroblast by loss of H3K27me3.、Maeda M, Gut. 、2019
  • F-Box/WD Repeat Domain-Containing 7 Induces Chemotherapy Resistance in Colorectal Cancer Stem Cells.、Honma S, Cancers(Basel)、11(635),2019
  • Antiadhesion effect of the C17 glycerin ester of isoprenoid-type lipid forming a nonlamellar liquid crystal.、Murakami T、Acta Biomater.、85,257-267,2019
  • Robotic versus laparoscopic surgery for rectal cancer: an overview of systematic reviews with quality assessment of current evidence.、Hoshino N, Surg Today.、
  • Short-term outcomes of laparoscopic surgery for colorectal cancer in the elderly versus non-elderly: a systematic review and meta-analysis.、Hoshino N, Int J Colorectal Dis、34(3),377-386,2019
  • Optimal treatment strategy for rectal cancer based on the risk factors for recurrence patterns.、Yamamoto T, Int J Clin Oncol、24(6),677-685,2019
  • The Role of Tumor-Associated Neutrophils in Colorectal Cancer.、Mizuno R, Int J Mol Sci、20(3),529,2019
  • Three-dimensional Stereoscopic Visualization Shortens Operative Time in Laparoscopic Gastrectomy for Gastric Cancer.、Itatani Y, Sci Rep.、9(1),4108,2019
  • Intraperitoneal chemotherapy for peritoneal metastases using sustained release formula of cisplatin-incorporated gelatin hydrogel granules.、Yamashita K, Surg Today、
  • Loss of SMAD4 Promotes Colorectal Cancer Progression by Recruiting Tumor-Associated Neutrophils via the CXCL1/8-CXCR2 Axis.、Ogawa R, Clin Cancer Res、25(9),2887-2899,2019
  • Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression via CCR5.、Nishikawa G、Cell Death Dis.、10(4),264,2019
  • Laparoscopic distal gastrectomy for gastric cancer patient with intestinal malrotation: report of a case.、Inamoto S, Surg Case Rep.、5(1),45,2019
  • Feasibility of robotic radical gastrectomy using a monopolar device for gastric cancer.、Okabe H, Surg Today.、2019
  • Combined laparoscopic and cystoscopic surgery for colovesical fistula due to colonic diverticulitis.、Kawada K, Tech Coloproctol.、2019
  • A randomized phase study of s-1 adjuvant chemotherapy with or without Hochu-ekki-to, a Japanese herbal medicine, for stage Ⅱ/Ⅲ gastric cancer: The KUGC07(SHOT) trial.、Okabe H, Frontiers in Oncology、2019
  • Mesenteric excision of upper esophagus: a concept for rational anatomical lymphadenectomy of the recurrent laryngeal nodes in thoracoscopic esophagectomy.、Tsunoda S, Surgical Endoscopy、2019
  • Revisiting the infracardiac bursa using multimodal methods: topographic anatomy for surgery of the esophagogastric junction.、Nakamura T, J Anat. 、235(1),88-95,2019
  • “Prognostic impact of the combination of neutrophil-to-lymphocyte ratio and Glasgow prognostic score in colorectal cancer: a retrospective cohort study、Inamoto S, Int J Colorectal Dis.、34(7),1303-1315,2019″
  • Simultaneous robotic surgery with low anterior resection and prostatectomy/hysterectomy、Itatani Y, Int Cancer Conf J. 、8(4),141-145,2019
  • Diagnostic accuracy of computed tomography colonography for tumor depth in colorectal cancer: A systematic review and meta-analysis 、Hoshino N, Surg Oncol. 、30,126-130,2019
  • Precise Three-Dimensional Morphology of the Male Anterior Anorectum Reconstructed From Large Serial Histologic Sections: A Cadaveric Study、Okada T, Dis Colon Rectum. 、62(10),1238-1247,2019
  • Indocyanine Green Fluorescence-Guided Laparoscopic Lateral Lymph Node Dissection for Rectal Cancer.、Kawada K, Dis Colon Rectum. 、62(11),1401,2019
  • Transforming Growth Factor-β Signaling Pathway in Colorectal Cancer and Its Tumor Microenvironment.、Itatani Y, Int J Mol Sci、20(23),5822,2019
  • MicroRNA-9-5p-CDX2 Axis: A Useful Prognostic Biomarker for Patients with Stage II/III Colorectal Cancer、Nishiuchi A, Cancers (Basel).、11(12),1891,2019
  • “Linear or circular stapler? A propensity score‑matched, multicenter analysis of intracorporeal esophagojejunostomy following totally laparoscopic total gastrectomy、Murakami K, Surg Endosc.、2019″
  • Prostaglandin E2/EP Signaling in the Tumor Microenvironment of Colorectal Cancer、Mizuno R, Int J Mol Sci.、20(24),6254,2019
  • Hydrodynamic stress stimulates growth of cell clusters via the ANXA1/PI3K/AKT axis in colorectal 、Hagihara T, Sci Rep.、9(1),2019
  • “MicroRNA-9-5p-CDX2 Axis: A Useful Prognostic Biomarker for Patients with Stage II/III Colorectal Cancer、Nishiuchi A, Cancers (Basel).、11(12),2019″
  • “The Incidence of Postoperative Complications after Gastrectomy IncreasesinProportiontotheAmountofPreoperativeVisceralFat、Okada K, JournalofOncology、2019″
  • Real-World Situation of Lateral Lymph Node Dissection for Rectal Cancer in Japan.、Sakai Y, Dis Colon Rectum、62(6),2019
  • Targeting fusions for improved outcomes in oncology treatment、Nikanjam M and Okamura R, (contributed equally)、Cancer、126(6),1315-1321,2019
  • Clinical Correlates of Blood-derived Circulating Tumor DNA in Pancreatic Cancer、Patel H and Okamura R , (contributed equally)、Journal of Hematology and Oncology、12(1),130,2019
  • Iatrogenic diaphragmatic hernia as a late complication of laparoscopic excisional biopsy of peritoneal nodules: A case report.、Hashimoto K, Int J Surg Case Rep、67,169-172,2019

2018年

  • Impact of transanal drainage tube on anastomotic leakage after laparoscopic low anterior resection.、Kawada K, Int J Colorectal Dis. 、33(3):337-340、2018
  • Resistance to Anti-Angiogenic Therapy in Cancer-Alterations to Anti-VEGF Pathway.、Itatani Y, Int J Mol Sci、19(4):1232,2018
  • Proposal of a stage-specific surveillance strategy for colorectal cancer patients: A retrospective analysis of Japanese large cohort.、Okamura R, Eur J Surg Oncol. 、44(4):449-455,2018
  • Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery.、Hoshino N, Cochrane Database Syst Rev.、2018
  • Enhanced anastomotic healing by Daikenchuto (TJ-100) in rats.、Wada T、Sci Rep、8(1):1091,2018
    Treatment of Elderly Patients with Colorectal Cancer.、Itatani Y, Biomed Res Int.、2018
  • Efficacy of Endoscopic Management for Early Remnant Gastric Cancer: Is Completion Gastrectomy Truly Necessary in Cases with Marginally Noncurative Histopathologic Features?、Fukui Y, Ann Surg Oncol、25(6):1608-1615,2018
  • Novel epigenetic markers for gastric cancer risk stratification in individuals after Helicobacter pylori eradication.、Maeda M, Gastric Cancer、2018
  • Nomogram for predicting anastomotic leakage after low anterior resection for rectal cancer.、Hoshino N, Int J Colorectal Dis、33(4):411-418,2018
  • A novel use of indocyanine green to identify the plane of dissection during abdominoperineal resection by the transperineal approach – a video vignette.、Kawada K, Colorectal Dis. 、20(5):455-456,2018
  • A comparison of the long-term anorectal function between laparoscopic intersphincteric resection and low anterior resection for low rectal cancer.、Kawada K、Surg Today.、48(10):921-927,2018
  • Goshajinkigan for reducing chemotherapy-induced peripheral neuropathy: a systematic review and meta-analysis.、Hoshino N, Int J Clin Oncol、23(3):434-442,2018
  • Impact of drain insertion after perforated peptic ulcer repair in a Japanese nationwide database analysis.、Okumura K、World J Surg 、42:758-765,2018
  • Long-term oncologic outcomes of robotic gastrectomy for gastric cancer compared with laparoscopic gastrectomy. 、Obama K, Gastric Cancer、21(2):285-295,2018
  • Use of a lighted stent to identify the urethra during transanal abdominoperineal resection、Kawada K, Tech Coloproctol.、22(6):467-468,2018
  • The molecular basis and therapeutic potential of LET-7 microRNAs against colorectal cancer、Mizuno R, Can J Gastroenterol Hepatol.、2018
  • “Regulatory T cells with superior immunosuppressive capacity emigrate from the inflamed colon to draining lymph nodes.、Nakanishi Y, Mucosal Immunol.Mucosal Immunol. 、11(2):437-448,2018″
  • A cadaveric demonstration of visualization of urethra using a lighted stent during transanal intersphincteric resection. Okada T, International Cancer Conference journal 、7(3):77-80,2018
  • Roux-en-Y versus Billroth-I reconstruction after distal gastrectomy for gastric cancer (protocol).、Nishizaki D, Cochrane Library、2018
  • Transanal minimally invasive surgery for local excision of early rectal tumor.、Yoshitomi M, Asian J Endosc Surg. 、11(2):182-184,2018
  • Open versus Laparoscopic Surgery for Advanced Low Rectal Cancer: A Large, Multicenter, Propensity Score Matched Cohort Study in Japan.、Hida K, Annals of Surgery、268(2):318-324,2018
  • Laparoscopic rectal tumor surgery after administration of a new sclerosing therapy (aluminum potassium sulfate and tannic acid injection) for internal hemorrhoids: A report of three cases.、Goto S, Asian J Endosc Surg、Nov 8. doi: 10.1111/ases.12664. [Epub ahead of print]、2018
  • A Chemosensitivity Study of Colorectal Cancer Using Xenografts of Patient-Derived Tumor-Initiating Cells.、Maekawa H, Mol Cancer Ther.、17(10):2187-2196,2018
  • Optimal Cutoff Values of Skeletal Muscle Index to Define Sarcopenia for Prediction of Survival in Patients with Advanced Gastric Cancer.、Nishigori T, Ann Surg Oncol.、25(12):3596-3603,2018
  • Rikkunshito for upper gastrointestinal symptoms: A systematic review and meta-analysis.、Hoshino N, Complement Ther Med.、42:255-263,2018
  • Accurate diagnosis of mismatch repair deficiency in colorectal cancer using high-quality DNA samples from cultured stem cells.、Yamaura T, Oncotarget.、9(101):37534-37548,2018
  • Analysis of NTRK Alterations in 13,467 Pan-cancer Adult and Pediatric Malignancies; Implications for NTRK-targeted Therapeutics、Okamura R, JCO Precision Oncology、2018
  • Analysis of Circulating Tumor DNA and Clinical Correlates in Patients with Esophageal, Gastroesophageal Junction and Gastric Adenocarcinoma、Kato S, Okamura R (contributed equally)、Clinical Cancer Research、24(24):6248-6256,2018
  • ASO Author Reflections: Endoscopic Management Will Be an Effective Treatment Option for Early Remnant Gastric Cancer, Similar to Primary Gastric Cancer、Fukui Y, Ann Surg Oncol、25(Suppl3):743-744,2018
  • Laparoscopic intersphincteric resection of rectal cancer with posterior vaginal wall excision without hysterectomy.、Fukui Y, Tech Coloproctol、22(9) :719-724,2018